Transplant of Limbal Epithelial Stem Cells on Bioresorbable Scaffold
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چکیده
منابع مشابه
design of polycaprolactone nanofibrous scaffold as suitable substrate for limbal stem cells for corneal epithelial regeneration
purpose: to develop a nanofibrous polycaprolacton (pcl) substrate for limbal stem cell (lsc) expansion that can serve as a potential alternative substrate to replace human amniotic membrane. methods: the human limbal stem cells (lscs) were used to evaluate the biocompatibility of substrates (nanofibrous scaffold, and human amniotic membrane) regarding cellular phenotypic profile, viability, pro...
متن کاملThe phenotype of limbal epithelial stem cells.
PURPOSE The purpose of this study was to identify phenotypic markers of human limbal stem cells in fetal and adult corneas. METHODS RNA from microscopically dissected superficial limbal and central fetal (18 weeks) corneas was amplified and used to generate P(32)-labeled, reverse-transcribed antisense RNA that was linearly amplified and hybridized to a focused stem cell cDNA microarray. Diffe...
متن کاملLimbal epithelial stem cells of the cornea∗
1. Function and structure of the cornea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. Corneal development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 3. The stroma and endothelium . . . . . . . . . . . . . . . . . . . . ...
متن کاملA Biomimetic Compressed Collagen Scaffold for Cultured Limbal Epithelial Cells
Galway, Ireland A Biomimetic Compressed Collagen Scaffold for Cultured Limbal Epithelial Cells Hannah J Levis, Robert A Brown, Frank Tully, Julie Daniels. Corresponding Author: [email protected] Ocular Biology & Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom; UCL Tissue Regeneration and Engineering Centre, London, United Kingdom; The Automation Partnership, Hertfordshire, ...
متن کاملSurvival of donor epithelial cells after limbal stem cell transplantation.
PURPOSE To determine the long-term fate of donor epithelial cells after limbal allograft transplantation. METHODS Corneal buttons and peripheral blood leukocytes were obtained at the time of penetrating keratoplasty from three patients who had undergone a successful limbal allograft transplantation. Microdissection was used to remove the corneal epithelial cells from the button. The presence ...
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ژورنال
عنوان ژورنال: Sovremennye tehnologii v medicine
سال: 2017
ISSN: 2076-4243
DOI: 10.17691/stm2017.9.4.05